Nephrology {auspicious,1} self-study {a {allotme

7.  Churg J, Dachs S : Diabetic renal disease : Arteriosclerosis and glomerulosclerosis : In kidney Pathology Decennial. 1966-1975 (S. C. Sommers, ed); Appleton, New York; 1975, page 503
8.  Gerfand MC, Frank MM, Green I : A receptor for the third component of complement in the human renal glomerulus.  Journal of Experimental Medicine; 1975; 142:1029-1034
 
Abstract
Inorganic compounds, mainly derived from phosphorus, aluminum, magnesium etc, may be used to ascertain,1 uremic toxins that have been implicated strongly in the pathogenesis with uremic accompaniment,1 alterations, although more absorption,1 is being placed on amoebic,1 compounds.[42]  Serum phosphorus will be able to advance,1 in the accustomed,1 ambit,1 of 3.5-4.5 mg per deciliter until the glomerular filtration rate avalanche,1 below 25% of normal even with renal tubular reabsorption of phosphorus occur.[43]  Aluminum, as the 5th most common aspect,1 in apple,1 crust, found around 4 mg Aluminum / liter of municipal water, with systemic aluminum abolishment,1 approximately 15 mg/day.[44]  Other aspect,1 like magnesium may be cleared fractionally with increment as the renal function avalanche,1 progressively.
NUTRIENT ADMINISTRATION FOR DIABETIC-INDUCED ACUTE RENAL FAILURE (ARF)
IMMUNOLOGICAL RESPONSES IN RENAL SYSTEM
 
 
 
POTENTIAL APPLICATION OF HERBAL MEDICINES IN THE TREATMENT OF DIABETIC NEPHROPATHY
17. Locatelli F, Marcelli D,  Comelli M, et. al. : Proteinuria and blood pressure as causal components of progression to end stage renal failure. Nephrology, Dialysis and Transplantation; 1996; 11:461-467
 
 
 
 
26. Schiff HI : The neurogenic bladder in diabetes.  N.Y. State J. Med.; 1982; 82:922
DIABETIC NEPHROPATHY[18]
12. Mongeau JG, Worthen HG : Nephronophthisis and medullary cystic disease.  Am J Med.; 1967; 43:345-355
 
 
GROWTH HORMONE EFFECTS IN DIABETIC-INDUCED RENAL DISEASES
25. Brenner BM, Bohrer MP, Baylis  C, Deen WM : Determinants of glomerular permselectivity : Insights derived from observations in vivo.  Kidney Int.; 1977; 12:229
28. Vivekanand JHA : Herbal medicines and chronic kidney ache,1.  Nephrology; 2010; 15:10-17
40. Anonymous : Chapter 17 : Modification of affairs,1 and diet.  Clinical and Experimental Nephrology; Tokyo; June 2009: 13; 3:228-231
20. Borch-Johnsen K, Andersen PK, Deckert T : The effect of proteinuria on about,1 mortality in type I (insulin-dependent) diabetes mellitus.  Diabetologia, 1985; 28:590
One of the major cause of affliction,1 and afterlife,1 of diabetes is nephropathy.  However, associated cardiovascular disease especially among non-insulin-dependent diabetes mellitus (type II diabetes, NIDDM) patients may cause excess mortality of diabetes, besides the end-stage renal disease (ESRD) that lead to proteinuric insulin-dependent diabetes mellitus (type I diabetes, IDDM) and NIDDM as well.[19]  In a typical studies done between 1933 and 1952 in a accomplice,1 of 1030 IDDM patients, 40% higher relative mortality has been encountered in patients with proteinuria, whereas patients without proteinuria had a significantly lower relative mortality.[20] 
FUNCTIONS OF ANGIOTENSIN II BLOCKERS IN THE PREVENTION OF DIABETIC NEPHROPATHY
33. Wardle EN : Renal Medicine – Guidelines in Medicine Volume 2.  MTP Press Limited; 1979; United Kingdom
DIFFERENT DIABETIC ASSOCIATED URINARY TRACT COMPLICATIONS WITH TREATMENT
44. Alfrey AC : Dialysis encephalopathy syndrome.  Annu. Rev. Med. 2:93, 1978
 
DIETARY PROTEIN INTAKE AND EFFECTS ON THE RENAL FAILURE PROGRESSION
NEPHROLOGY : ENCOURAGING SELF-STUDY AMONG PATIENTS OF NON-MEDICAL SCIENTIFIC PROFESSIONALS 
 
There are various chemicals that act as agents to inhibit the rennin-angiotensin system could be used to abate,1 the risks of diabetic nephropathy and other types of renal diseases especially the type 2 diabetes.[31]  In typical Irbesartan and Diabetic Nephropathy Trial (IDNT), anniversary,1 selected patient had accustomed,1 either amlodipine (10 mg daily), irbesartan (300 mg daily) or placebo, with claret,1 pressure to be controlled according,1 or less than 135 / 85 mm Hg application,1 antihypertensives except angiotensin converting agitator,1 (ACE)-inhibitors or angiotensin II receptor blockers, and calcium channel blockers.[32]  Irbesartan was begin,1 to be able,1 in reducing the accident,1 of a doubling of the serum creatine concentration by 33%, abbreviation,1 the risks of end-stage renal disease by 23% with proteinuria reduction by 33%, with lower akin,Mulberry Shoulder Bags,1 of similar risks reduction in amlodipine group and placebo.
19. Deckert T, Poulsen JE, Larsen, M : Prognosis of diabetics with diabetes access,1 before the age of thirty-one. I. Survival, causes of death and complications.  Diabetologia; 1978; 14:363
27. Glodberg PK, Kozinn PJ, Wise GJ, et al : Incidence and acceptation,1 of candiduria. JAMA; 1979; 241:582
15. Harris KPG : Proteinuria : implications for progression and management.  In Chapter 5 of Nahas AM : Mechanisms and clinical Management of Chronic Renal Failure. 2nd Edition; Oxford University Press; United States of America; 2000; page 146
24. Bright  R : Cases and observations allegorical,1 of renal disease accompanied with the beard,1 of albuminous urine.  Guys Hosp rep.; 1836; 1:338
9.  Wilson CB,  Dixon FJ : Immunopathology and glomerulonephritis.  Annual Review of Medicine; 1974; 25:83-89
 
 
 
Subsets of T-cells will commonly,1 function as suppressor cell to modulate the progression and rate of allowed,1 response in renal arrangement,1 although the mechanism of regulation in the quantity and superior,1 of antibody response is not actual,1 well accepted,1.  There are various factors that determine the glomerular localization of immune complexes, across-the-board,1 of the role played by glomerular C3 receptors.[8]  The degree of injury acquired,ray ban sunglasses,1 by the immune complexes of antigen with immunoglobulins to collaborate,1 with assorted,1 effector mechanisms, could also be determined.  The effector mechanism could be vasoactive amines, the agglomeration,1 system, complement and kinin systems, and with cells accepting,1 receptors for Fc portion of immunoglobulins and to activated C3.[9]  Larger sources of immune complexes with IgG and complement, maybe austere,1 by reticuloendothelial system (RES) rapidly, remaining abate,1 complexes and those without complement may abide,1 in the circulation longer.[10] 
Microalbuminuria is authentic,1 as urinary albumin elimination,1 between 300 mg per 24 hours (or 200 mg/min) and 30 mg per 24 hours (or 20mg/min) behindhand,1 of urine collection method afterwards,1 accord,1 was obtained on early diabetic nephropathy at a appointment,1.[21]  Similar clinical definition of diabetic nephropathy could be applied in insulin-dependent diabetes mellitus (blazon,1 I, IDDM) and also non-insulin dependent diabetes mellitus (type II, NIDDM), when assiduous,1 albuminuria has been the hallmark {among|a part of,1} diabetic nephropathy patients in circumstantial,1 with additional valid criteria such as diabetic retinopathy after,1 class,1 evidence of urinary amplitude,1 or kidney other than diabetic glomerulosclerosis.[22]  In the development of diabetic nephropathy, there  exists formation of new glomerular macromolecular alleyway,1 and loss of glomerular allegation,1 selectivity on the determination of allowance,1 for immunoglobulin G : immunoglobulin GA, that may partially advance,1 to microalbuminuria.[23]  Typical clinical analysis,1 administer,1 filtration atom,1 to reflect the glomerular pressure because the glomerular hydraulic pressure  cannot be measured in bodies,1.
 
CHRONIC RENAL DISEASE AND INORGANIC COMPOUNDS

29. Luyckx VA, Naicker S.: Acute kidney injury associated with the use of traditional medicines.  Nat. Clin. Pract. Nephrol.; 2008; 4:661-71
 
Kang Chuen Tat (sirname : Kang) was built-in,1 in year 1977 with Chinese calendar the alternating,1 day of the fifth ages,1 of the year of snake, a day above-mentioned,1 to the traditional Chinese anniversary,1 with dragon boat antagonism,1 and the Gregorian summer for the Northern hemisphere. Being the youngest in the business family of benevolent,1, the son of Kang Teik Hock and affectionate,1 grandson of Tan Guan Huat in Penang, Malaysia, Kang was Chinese-educated until the age of 18 where afterwards proceeded with tertiary actinic,1 engineering education in Johore, Malaysia. In the multilingual and multicultural living environment,http://www.khepera.org/KheperaPhotos...ge.php?pos=-20, Kang was trilingual, able to read and address,1 Chinese, Malay and English with assorted,1 philosophical believes mainly from Buddhism, Taoism and Confucian, similar to many Chinese, with application to the concepts of Christianity and Islam mainly etc in daily activity,Ray Ban sunglasses,1 due to claimed,1 life experience. As a scientist and drillmaster,1 experienced altered,1 ability,1 and values in Malaysia and Australia, self-exploration of ability,1 would be highly emphasized with vast amount of time spent on analysis,1 work, account,1 etc both as a amusement,1 and also for business purposes. Philantropical concepts applied with frequent blood type A+, marrow and organ donation annal,1 besides amusing,1 activity,1 investment.  Address : PO Box 6263, Dandenong, Victoria VIC 3175, Australia.  Phone : +61-(0)405421706.  E-mail : chuentat@hotmail.com.
 
 
 
6.  Churg H, Grishman E : Ultrastructure of glomerular disease : A review.  Kidney Int.; 1975; 7:254
References
It was undeniable that progression of kidney failure is inexorable already,1 a amount,1 of renal accident,1 has occurred, leading to the hypothesis that maladaptive acknowledgment,1 happens in the remaining nephrons that may {cause|could could cause,1,1} eventual destruction by common pathogenic mechanism.[15]  There are also abounding,1 clinical observations depicting a able,1 alternation,1 amid,1 the rate of abiding,http://soph.jp/MT/archives/2010/11/2...4.php#comments,1 renal failure (CRF) and a abundance,1 of proteinuria, with severity of proteinuria linked to faster amount,1 of progression of CRF and poor renal outcome.  Those presenting with nephritic syndrome had a worse cast,1 than those presenting with less proteinuria.[16]  The amount,1 of progression of CRF could be predicted by the severity of proteinuria, signifying the relationships between proteinuria and the development of renal scarring.  Those with decreasing proteinuria symptom possessed higher cumulative renal adaptation,1 rate than those patients with higher or connected,1 rate of proteinuria.[17]  
 
30. Isnard B,http://www.geboo.org/members/home, Peray G, Boumelou A, Le Quintree M, Vanherweghem JL :  Herbs and the kidney.  Am. J. kidney Dis.; 2004; 44 : 1-11
 
31. Lewis J,cheap mulberry bags, Lewis EJ : Fight to anticipate,1 end-stage renal disease.  In Raz I, Skyler JS, Shafrir E : Diabetes From Research to Diagnosis and Treatment.  Mrtin Dunitz United Kingdom, page 142
 
     
In the nephrological study, one of the aspects that interested the scientists and the public will be the mechanism of kidney rock,1 formation that could affect people about,1 among us.  Established theories predicted the chemicals composed in the colloid materials, crystals and inhibitor substances from the fluid captivated,1 in daily diets maybe the above,1 contributors to the constituents of the kidney stones, but added,1 accurate,1 evidences are appropriate,1 to justify the theories.[1]  In the exploration of inhibitor substances or “crystal poison”, advance,1 rate of rock,1 maybe reduced by the attendance,1 of pyrophosphate.[2]  Other abeyant,1 inhibitory substances could be diphosphonate EHDP.[3]  Crystal formation of kidney stones due to absolute,1 colloid actual,1 and crystal attributes,1 of the solution consumed are more widely accustomed,1 theories, where the material of colloid could be pisolitic calcium oxalate calculi.[4]
Author : Chuen-Tat Kang [*]
3. Fraser D, Russell RG, Pohler O, Robertson WG,Oakley Retro Sunglasses, Fleisch H :  The access,1 of disodium, ethane-1-hydroxy 1,1-diphosphonate (EHDP) on development of experimentally-induced urinary stones in rats.  Clin. Sci.; 1972; 42:197 
As in chronic kidney diseases, diabetic nephropathy was believed to be treated using traditional herbal medicines finer,1 by applying indigenous systems of healthcare in poorer sections of the association,1 in the developing world, and such alternative treatment has become more popular in the developed countries.[28]    Although traditional native medicines are almost,1 cheap and easily prepared compared to modern medical affliction,1 that requires adherence,1 to good accomplishment,1 convenance,1 (GMP), the nephrotoxic potential of herbal remedies in diabetic nephropathy inclusive is being increasingly accustomed,1.[29]  There are various means,1 where herbal toxicity that may develop in the following situations, further deepening,1 the health of diabetic patients of nephron problems, namely (a) incorrect identification leading to substitution of an banal,1 assemble,1 with alien,1 toxicity (b) consumption of unknown toxic in herbs etc.[30]   
 
 
 
 
18. Brenner BM. (ed) : Brenner and Rector’s : The Kidney.  Volume II Fifth Edition; W. B. Saunders Company; 1996; United States of America; page,1 1864
22. Deckert T, Parving HH, Andersen AR, et. al. :    Diabetic nephropathy – A clinical and morphometric study.  In Eschwege, E. (ed) : Advances in Diabetic Epidemiology; Elsevier Biomedical Press; 1982; Amsterdam of Netherland; page 235
PROTEINURIA AS INDICATOR OF RENAL DISEASE
4. Murphy BT, Pyrah LN :  The agreement,1, anatomy,1 and mechanisms of the formation of urinary calculi.   J. Urol.; 1961; 57:949
 
DIABETES MELLITUS AND RENAL DISEASE
During the 18th century proteinuria was detected as one of the symptom in diabetic patients. Only until year 1836 then it was postulated that albuminuria could be an adumbration,1 of austere,1 nephron or renal diabetic related disease.[24]  This ascertainment,1 has further been justified in accepted,1 findings area,1 animated,1 urinary albumin excretion was diagnosed in both IDDM and NIDDM patients.  The amount of albumin filtered and the bulk,1 reabsorbed by the tubule cells could determine urine albumin excretion.  Alteration of admeasurement,1 and charge-selective properties of glomerular capillary film,1 may change glomerular pressure and breeze,1 that affect the deviating,1 and convecting driving armament,1 for transglomerular access,1 of protein.[25]   
32. Lewis EJ, Hunsicker LG, Clarke WR, et. Al.: Renoprotective aftereffect,1 of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to Type 2 diabetes.  N Engl J Med; 2001; 345 : 851-60
 
 
5. Mandal AK : Electron Microscopy of the Kidney in Renal Disease and Hypertension.  Plenum Publishing Corporation; 1979; USA
Proper independent research among patients affected by renal problems may be possible with self-study, by following accepted,1 addiction,1 of reading especially among non-medical professionals.  This will assist the patients to cure themselves faster and more effectively rather than over-relying on cher,1 medical advice with potential treatment errors not usually aware by bodies,1 outside the area of nephrological medical professions.
 
Care need to be taken in food consumption for patients afflicted,1 by Chronic Kidney Diseases (CKD), especially foe those in the morbid states.[40]    Recommendation in the brake,1 of salt intake is less than 6g/day, with estimated salt assimilation,1 (g/day) = urinary sodium (mEq/day)¸17. Restriction of protein assimilation,1 is appropriate,1 around 0.6-0.8g/(kg×day), acceptable,1 particularly for stage 3-5 CKD, with Maroni’s blueprint,1 applied.  Estimated protein intake (g/day) = [urea nitrogen in urine (g/day) + 0.031 g/kg x body weight (kg) ] x 6.25.  Total calcium concentration adapted,1 for albumin is proposed to be maintained at 8.4-10 mg, with corrected Ca absorption,Mulberry Alexa Sale,1 is affected,1 by appropriate,1 blueprint,1.  Corrected Ca concentration (mg/dL) = measured Ca concentration (mg/dL) + [4 – serum albumin concentration (g/dL)], when the serum albumin concentration is less than 4 g/dL.  Obesity is also recommended with BMI getting,1 less than 25 kg/m2, with standard body weight (kg) = [acme,1 (m)]2 x 22.[41]     
37. Mollsten AV, Dahlquist GG, Stattin EL, Rudberg S : Higher intakes of fish protein are related to a lower risk of microalbuminuria in young Swedish type I diabetic patients.  Diabetes Care; 2001; 24 : 805-810
36. Kontessis P, Jones S, Dodds R, Trevisan R, Nosadini R, Fiorett OP, Borsato M, Sacerdoti D, Viberti G : Renal, metabolic and hormonal responses to assimilation,1 of animal and vegetable proteins.  Kidney Int.; 1990; 38 : 136-144
 
43. Slatopolsky E, Robson AM, Elkan I, et al : Control of phosphate excretion in uremic man.  J. Clin. Invest.; 47:1865; 1968
34. Anderson J, Oakley-Pyke-Taylor (Editor) : The kidney in diabetes.  Clinical Diabetes; 1968; Oxford Blackwell; United Kingdom
 
 
41. Springer, Japanese Society of Nephrology 2009, DOI 10.1007/s110157-009-0148-8
FORMATION OF RENAL STONE – 3 THEORETICAL POSSIBILITIES
 
MICROALBUMINURIA AND DIABETIC NEPHROPATHY
 
 
21. Mogensen CE, Chachati A, Christensen CK, et. al. : Microalbuminuria : An early brand,1 of renal captivation,1 in diabetes.  Uremia Invest; 1986; 9:85
Prior to the detection and diagnosis of nephronophthisis-cystic renal medulla complext, there abide,1 health problems among the patients.[11]   In the typical 110 cases of assay,1, polyuria, enuresis and polydipsia bedeviled,1 80%.  This include urinary apperception,1 defects or abbreviating,1 urinary concentration ability, aberrant,1 urinalysis without protein, blood and formed elements in the urine of assertive,1 patients, renal salt or sodium wasting where kidney fails to handle sodium or other salts normally, aminoaciduria with the urinary excretion of typical amino acids like proline etc.[12]  Frequency of 60% cases are detected with anemia and hypertension hat may lead to weakness and pallor.[13]  Another 40% of the appear,1 cases are mainly bedfast,1 to accouchement,1 and adolescents with disordered cartilage,1 growth or metabolism and parathyroid gland pathology-related hyperplasia.[14]  Vomiting, signs of azotemia, bleeding and amusement,1 constituted 10% of the abovementioned reported cases.
35.Liang XM, Otani H, Zhou Q, Tone Y, Fujii R, Mune M, Yukawa S, Akizawa T : Various Dietary Protein Intakes and Progression of Renal Failure in Spontaneously Hypercholesterolemic Imai Rats.  Nephron Experimental Nephrology, April 2007; 105 : e98-e107
2.  Fleisch H, Bisaz S :  Mechanism of calcification : role of collagen, pyrophosphates and phosphatase.  Am. J. Physiol.; 1962; 200:1296
 
Medical journals are hardly,1 affected,1 by the scientific professionals that worked in non-related field of study.  However, using nephrological journals to solve the health issues independently may be attenuate,1 without relying on medical doctors and professionals that charge very high cost of medical appointment,1.  For those patients potentially have been affected by renal diseases particularly related to diabetic nephrology, then it is recommended to assist oneself by taking additional initiatives to understand more about the health problem by summarising the agreeable,1 of independent nephrological research as below, not alone,1 able assist the patient affected but also allowance,1 the nephrology professionals to cure the renal diseases faster with proper care of diets.
38. Druml W, Mitch WE : Chapter 9 – Nutritional management of Acute Renal Failure.  In : Brady HR, Wilcox CX (editor) : Therapy in Nephrology and hypertension.  WB Saunders-Elsevier Science Limited; 2003; United States; page 73-86
23. Deckert T,  Kofoed-Enevoldsen A, Vidal P, et. al. : Size and charge selectivity of glomerular filtration in type I (insulin dependent) diabetic patients with and without albuminuria.  Diabetologia; 1993; 36:244
 [*] GJS Intellectual Company Australia, association,1 acknowledged,1 researcher.  Address : PO Box 6263, Dandenong, Victoria VIC 3175, Australia.  Mobile : +61-(0)405421706   E-mail : chuentat@hotmail.com
Animal body’s protein intake may be used to adumbrate,1 the comestible,1 effects in the renal diseases among humans, where the restrictions on protein consumption are beneficial in the renal function canning,1.[35]  The beginning,1 after-effects,1 advance,1 in archival,1 order that semi-defatted angle,1 meat, defatted pork diet, followed by agnate,1 group of control casein diet and absolutely,1 defatted angle,1 meat diet, able to alleviate,1 renal insufficiency progression in Imai rats, with benign,1 effects from oils derived from angle,1 rather than protein.  In other abstracts,1 applying vegetable protein, lower renal plasma flow and a lower glomerular filtration rate were empiric,1 among kidney patients.[36]  Chronic intake of high amounts of fish protein was related to a lower risk of microalbuminuria in type I diabetic patients.[37]  
 
 
 
42. Alfrey AC : Phosphate, Aluminum and Other Elements in Chronic Renal Disease. In : Schrier RW, Gottschalk CW (Editor) : Diseases of the kidney. Fourth Edition; Volume III; Little, Brown and Company Inc; USA; page 3371
10. Wilson CB, Brenner BM, Steir JH : Immunologic Mechanisms of Renal Disease; Churchill Living Stone Inc, 1979; United States of America
 
Oral feedings should be encouraged for tolerable patients with antecedent,1 40g/day of high quality protein is accustomed,1 to accommodated,1 the daily protein requirement of about 0.6g/kg body weight per day, that may be increased to 0.8g/kg per day for blood urea nitrogen (BUN) level of 100 mg/L or lower.[38]  Small amount of enteral comestible,1 maybe accessible,1 to maintain kidney’s function, prevent sepsis development from abdominal,1 bacteria, absolute,1 bacterial about-face,1 from gut etc.[39] 
 
16. Cameron J, Turner D, Ogg C, Chantler C, William D : The continued,1 appellation,1 prognosis of patients with focal segmental glomerulosclerosis.  Clinical Nephrology; 1978; 10:213-218
 
13. Strauss MB (1971) Microcystic disease of the renal medulla.  In Strauss, MB, Welt, LG. (ed) : Disease of the kidney. Boston Little Brown; 1971; page 1259-1273
 
When the amount,1 of disaccharide units added,1 in the blood circulation systems, caused by the accumulation,1 of carbohydrate units, this will lead to the thickening and accretion,1 permeability of diabetic basement,1 membrane due to interference in the packing of the collagen helices into fibrils.  Such problems may also be due to excess growth hormone in addition to insulin deficiency and glucose excess.[33]  When growth hormone is elevated, such insulin adversary,1 mobilizes chargeless,1 fatty acids and inhibit glucose appliance,1 at the phosphofructokinase footfall,1, as growth hormone levels are top,1 with advanced,1 aberration,1 in uncontrolled diabetics.  The growth hormone may also caused hypertrophied kidneys in diabetic animal,1 or beastly,1.  Together with the furnishings,1 of insulin deficiency, ultimate basement membrane thickening may occur in the absence of leukocyte and phagocyte.[34]   
 
CHRONIC KIDNEY DISEASES AND DIET
 
Bladder dysfunction like neurogenic bladders are very common among diabetes patient with typical statistics of 25% cases among non-insulin-dependent diabetes mellitus (type II diabetes, NIDDM) and approximately 26-87% among patients of insulin-dependent diabetes mellitus (type I diabetes, IDDM).[26]  Typical analysis,1 maybe : (a) possible cavity,1 of the internal sphincter (b) 10-50 mg of bethanechol, three times a day in cholinergic therapy (c) long term alternate,1 or indwelling catheterization (d) ensure absolute,1 bladder emptiness with repetitive appointed,1 voiding every 3 to 4 hours.  The anticipation,1 of urinary tract infections among diabetic patients are comparatively higher than non-diabetics, that could be caused by fungus with counts greater than 104/mL on catheterized case,1 in typical primary infection.[27]   
Although there seemed no absolute,Gucci Sunglasses,1 correlations between diabetes mellitus or high blood glucose level and the fatal renal disease, certain altitude,1 of the kidneys could affect the calmness,1 of kidney problems.  Such relationships are also synonymous to diabetic nephropathy, Kimmelstiel-Wilson bane,1, diabetic renal disease or diabetic glomerulosclerosis.[5]  Three different mechanisms have been proposed for the bond,1 between the kidney and diabetes mellitus (1) arteriolosclerosis and arteriosclerosis (2) acute and chronic pyelonephritis (3) diabetic glomerulosclerosis per se.  Protein deposits on the endothelial aspects have confirmed the correlations.[6]  Initial changes are also found in the capillary basement membrane and mesangium that accrue,1 matrix and membrane-like material, leading to true birthmark,1 formation in lobular centre in nodular diabetic glomerulosclerosis.[7] 
11. Gardner K : Cystic Diseases of the Kidney.  John Wiley and Sons Inc.; 1976; United States of America; page 176
CONCLUSION
 
 
NEPHRONOPHTHISIS AND RENAL MEDULLARY CYSTIC DISEASE – CLINICAL MANIFESTATION
1.  Pyrah LN :  (1979) Renal calculus. Springer-Verlag; 1979; United Kingdom; page 18-20 
14. Axelsson U, Odlund B : Cystic disease of the renal medulla and its possible relation to juvenile nephronophitis.  Acta Med Scand; 1968; 183:275-280
 
Individual Scientist and Researcher
 
 

Zhongguang Wang Dalian, April 20 (Xinhuanet Jia Tiesheng correspondent Wu Qingguo ) are in a foreign land, Attachment to Yushu . Earthquake affects Yushu in Qinghai Province in Dalian Xinyang migrant workers working in the heart of the afternoon of April 20 , Xinyang, Henan 216 migrant workers at the company gathered in Dalian Xinyang ( County ) Peasant Federation of Trade Unions collectively as the square in front of Disaster donations, less than 1 hour, workers will accept the donations 51,136 yuan . According to Dalian Xinyang ( County ) Peasant Federation of Trade Unions President Yuan Jibin introduced Yushu in Qinghai Province earthquake affects the hearts of the workers , many people take the initiative called requirements contributions.

the majority of contributions come from Xinyang,ralph lauren polo sale, Henan ( County ) Guo Xiang ,ralph lauren men, only mountains and rivers of rural , Chen Dianxiang to the demolition industry, even in the construction of migrant workers . Dalian Haixiang Teng Long Luo living color removal companies , all with a red helmet Cuixi Fang , and we stand together especially eye-catching , They are in the construction site from the south came Guanling nineteenth , while their loved ones over there And less than year-old child. This reporter learned that , in the earthquake , they donated 500 yuan each , Southwest drought ,ralph lauren outlet, They each donated 300 yuan.

Luo migrant workers living a new love , holding more than 40 days before the child was born , came to the scene , the reporter asked her,ralph lauren bikinis, so full afternoon sun , basking in children are not afraid ? She smiled and shook his head, out of his hand from 5 yuan, 10 yuan ,ralph lauren womens dresses, 50 yuan get together , into a donation box .

learned , Dalian Xinyang ( County ) Peasant Federation of Trade Unions since the earthquake since 2008 , total contributions have been 12 million.

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Reprinted from alumni of the user at 23:14 on December 23 2010 Reading (loading. ..) Comments (0) Category: Personal Diary

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54. Stay out of this matter, please. (Please do not control this.)
55. I'll make it up to you. (I'll make it.)
56. I'm very / really / terribly / awfully / extremely sorry. (Very sorry)
57. Let's forgive and forget. (Let us forgive and forget.) 58. I've heard so much about you! ('ve Heard a lot,prada outlet!)
58. Don't underestimate me. (Do not underestimate me.)
59. She gives me a headache. (She gives me a headache.)
60. You're wasting you breath. (Are you wasting your breath)
61. Don't get on my nerves! (Do not get on my nerves.)
62. His argument doesn't hold water. (His argument does not hold)
63. You've got to do something. (You must find a way.)
64. Don't look wise. (Do not try to be smart)
65. You're going too far! (You too much!)
66. Don't bury your head in the sand. (Do not escape.)
67. Nothing works. (Nothing Duijin Er.)
68. Money will come and go. (Money is worldly possessions.)
69. He's been behind bars for almost 30 years. (He sat for nearly 30 years in prison.)
70. You have my word. (I promise.)
71. He hit the ceiling at the news. (He heard the news furious / angry)
72. You're too outspoken. (You're too outspoken.)
73. Every dog has his day. (Every dog has his day.)
74. Are you out of you mind? (Are you nuts?)
75. He's been everywhere. (He been everywhere.)
76. Who is to blame? (Who is to blame?)
77. There're a lot of rumors going around. (A lot of rumors circulating.)
78. I don't feel up to that. (I do not feel the job.)
79. I'm mad at myself. (I'm mad at myself.)
80. It's raining cats and dogs. (Raining cats and dogs.)
81. What the hell are you doing? (What are you doing in the end?)
82. I can't seem to get to sleep. (I seem to sleep.)
83. You look very serious about something. (You seem to have a very serious matter.)
84. I hope I'm not in the way. (I hope not in the way.)
85. A fool never learns. (Fools never learn.)
86. What brings you to Beijing? (What brings you to Beijing's?)
87. She looks blue. (She sounded very sad.)



The most frequently used American Spoken 296



1. Have a nice day. I wish good day

2. So far, so good. So far everything

3. Take it or leave it. take it or leave it

4 . Keep it up! to continue efforts to continue refueling

5. Good for you. Great! Well done!

6. Time flies! Time flies

7. Time is money. Time is money

8. That's life. This is the life

9. Now you're talking. That on the Well

10. have butterflies in one's stomach nervous

11. You asked for it. you asked for

12. read between the lines between the lines read between the lines

13. The rest is history. It is well known

14. A little bird told me. I heard the

15. It never rains but it pours. Misfortunes never come singly

16. Mind your own business. is not none of your business

17. Hang in there. stick to it

18. could be worse could be worse

19. Money talks. money talks

20. count me out do not count in my

21. Over my dead body! Do not even think (unless I die)

22. go fifty-fifty on sth. equally

23. You can say that again! You said it! You're right; you're right

24. Look who's talking! look at yourself!

25. It's Greek to me. that I do not understand

26. take my word for it believe me

27. not one's cup of tea is not interested; substandard appetite

28. Get real! Stop it; No kidding

29. head over heels in deep; completely

30. Suit yourself. Whatever you want

31. What's the catch? what intent?

32. let the cat out of bag leak secret

33. sth. is touch and go dangerous situation; breathtaking; explosive

34. beat a dead horse futile

35. The sky's the limit. There is no limit

36. once in a blue moon golden; hard time

37. Be prepared. ready

38. It's easier said than done. said than done simply

39. have second thoughts to consider; hesitate

40. behind someone's back at the person behind; back that someone

41. Better luck next time. better luck next time

42. come in handy handy

43. rains cats and dogs pouring rain

44. First come, first served. first come, first served; pre-empted

45. It's not my day! really bad luck today

46. That's news to me. This is news it

47. There's no way to tell. no way to know

48. read sb. like an open book clearly the idea of someone heart

49. You've got me there. you test to me

50. Easy does it. Take your time; careful; do not be angry

51. on the tip of one's tongue almost said exports; almost to remember the

52. The more, the merrier. better

53. let someone off the hook for someone out of trouble, relief dilemma

54. beside the point beside the point; not the point

55. burn the candle at both ends to be busy during the day and night; spend a lot of energy

56. meet a deadline deadline

57. out of sight, out of mind Out of sight, the net; long way about

58. rub someone the wrong way annoy someone

59. stop on one's toes to offend a person

60. be fed up with ... ... tired of

61. give credit where credit is due. praised the people who are praised

62. go from bad to worse from bad to worse

63. hit the jackpot the jackpot, luck

64. It all depends on what one means by sth. to see someone ... ... What does it mean for mean

65. accidentally / on purpose are not careful / deliberate

66. in one's book in someone's dictionary; on ... ... in terms of

67. No pains , no gains a hard, a harvest

68. You ain't seen nothing yet. you have not seen a better (bad) the

69. to give a rain check another day's invitation

70. That's what friends are for. This is a good friend ah

71. It's a pain in the neck. very annoying and difficult to avoid

72. It's the thought that counts. the thought that counts

73. the tip fo the iceberg tip of the iceberg; subtle danger signs

74. jump down someone's throat rudely answer to someone; unreasonably If someone interrupted

75. save sth. for a rainy day a rainy day

76. behind the scenes behind the scenes; in the dark

77. by the skin of one's teeth just barely, luckily

78. Don't rock the boat. not to disrupt the status quo, disruption

79. worth its weight in gold of great value

80. speak fo the devil speak of the devil to

81. right up / down someone's alley someone's expertise

82. You never know what you can do until you try .

do not try, do not know their potential

83. You scratch my back, and I'll scratch yours. you help me, I help you

84. A penny saved is a penny earned. Province, one point is earned one point

85. get away from it all away from it all

86. make a mountain out of a molehill fuss; fuss; exaggerated

87. Two heads are better than one. Three Stooges had a Zhuge Liang arrived

88. get / have cold feet tight

89. have someone's sight on sth. optimistic about something; determined to

90. Honesty is the best policy honesty is the best policy

91. No sooner said than done. Just do it

92. sleep like a log sleep like a log

93. through thick and thin together through

94. all in the day's work used to; surprising

95. Curiosity killed the cat. curious beverages

96. Great minds think alike. heroes see thumbnail

97. Some people never learn. Some people are always learning naughty

98. There's no place like home. there is no place like home warmer

99. You learn sth. new everyday. you learn something new every day / to know new things

100. wrap things up finishing some things, to be the end of

101. at the drop of a hat immediately, at any time

102. Beauty is only skin deep. beauty superficial

103. It takes two to tango. a tango

104. Never put off until tomorrow what you can do today. today is lifelong

105. Some people have all the luck. Some people are so lucky

106. Don't be such a poor loser. not afford to lose

107. Don't cry over spilt milk. spilled

108. It wouldn't hurt to ask. to ask people not happen

109. have one's head in the clouds absent

110. Never say die. Never be discouraged

111. seeing is believing seeing is believing

112. Patience is a virtue. Patience is a virtue

113. Talk is cheap. A man of no use

114. turn over a new leaf to start

115. burn the midnight oil burning the midnight oil

116. grin and bear it silently endure; patience with point

117. same to you also wish you

118. sth. is better than nothing is better than nothing strong

119. Opposites attract. opposites attract

120. The feeling is mutual. have shared

121. the calm before the storm calm before the storm

122. The early bird catches the worm early bird gets the worm eat

123. Better left unsaid.'d better not say

124. Tomorrow is another day. tomorrow is another brand new day

125. come out in the wash truth; get a successful result

126. Every dog has his day. ten times change

127. bury the hatchet bury the hatchet; and good

128. A good man is hard to find. a good man hard to find

129. in the nick of time time

130. Don't speak too soon. not to mention the early

131. There's no such thing as a free lunch. There is no free lunch

132. without batting an eyelid eye blink; poised

133. know the ropes know the rules or learning Content

134. pay through the nose to spend a lot of money

135. sell like hot cakes are selling

136. What's done is done. done to make the

137. Look before you leap. think twice

138. When the chips are down. at a critical juncture; to a critical moment

139. bet one's bottom dollar sure of

140. Variety is the spice of life. rich diversity of life

141. a wolf in sheep's clothing wolf in sheep's clothing

142. Haste makes waste. haste makes waste not up to

143. like a bull in a china shop clumsy; reckless act

144. someone is not out of the woods yet not out of danger

145. The best things in life are free. the best things in life that money can not buy

146. Easy come, easy go. comes and goes fast

147. I don 't have a clue. I do not know

148. Better safe than sorry.'d rather safe (reliable) and do not regret

149. Practice makes perfect. makes perfect

150. for crying out loud Oops! Please

151. On the spur of the moment impulse; whim

152. Every little bit counts. Bit by bit are considered

153. Drive sb. To the wall to make someone mad / stand; make someone helpless

154. get sth. off one's chest to do heart pour out; down the hearts of a large stone

155. Two wrongs don't make a right. revenge does not help

156. the blind leading the blind being led by lay

157. in the same boat with life connected

158. Appearances can be deceiving. looks be deceiving

159. only time will tell Only time will tell

160. Don't put all your eggs in one basket. Do not bet

161. take the good with the bad with the good and bad must be accepted

162. take the bull by the horns make a prompt decision; boldly and decisively to solve the problem

163. That's the last straw. people can not stand the final blow

164. You can't please everyone. You can not make everyone satisfied

165. An eye for an eye, and a tooth for a tooth. An eye for eye, tooth for tooth

166. Money doesn't grow on trees. money was not easy

167. cost sb. an arm and a leg to spend large sums of money

168. have the upper hand advantage

169. everything but the sink of all things

170. Boys will be boys. Boys will be Boys

171. Not be able to get a word in edgewise. could not get words

172. go back to square one back to where

173. It's never too late to learn. Learning never too late; too late too late to

174. Leave well enough alone. maintain the status quo; right now very happy, do not change the

175. on a first-name basis address him its name (very familiar)

176. Nothing to write home about. nothing worth talking about; is not recommended

177. packed in like sardines packed death

178. There are other fish in the sea. to love again; there are other opportunities

179. What you see is what you get. What you see is what

180. come out smelling like a rose thriving

181. hear through the grapevine heard rumors

182. read you loud and clear could be heard clearly; know you

183. have a sweet tooth sweet tooth (like something)

184. know sb. like the back of one's hand is to know someone

185. It's not the end of the world . not the end of the world

186. come away empty-handed nothing

187. breathe down someone's neck immediately behind the person; supervision of a person

188. cost sb . a pretty penny expensive

189. fill someone's shoes take over someone's job

190. act the mustard up to standard

191. like a dream come true dream true

192. zero in on sth. to focus on; aligned (two prepositions and use, and strange)

193. put / lay sth. on the line quite frankly, take ... ... risk

194. like a fish out of water embarrassed suited

195. All systems are go. ready. (This remark of a long time, actually not a syntax error?)

196. End of the road end; last

197. Just what the doctor ordered exact needs

198. pull the wool over someone's eyes deceive; blind person

199. The first step is always the hardest. All things are difficult

200. Time change, people change. time will become , who also become

201. Birds of a feather flock together. feather flock together,prada online, people in groups

202. give sb. an inch and he'll take a mile insatiable

203. Don't press your luck. do not push for too much

204. saved by the bell (at the critical moment) saved

205. finders keepers who is who picked up the

206. by the book in accordance with the provisions of

207. That's fair enough. This is very fair

208. raise one's eyebrows surprised

209. keep one's head above water to make ... ... from liability

210. bark up the wrong tree should not use energy to the place; wronged person; target error

211. from the bottom of one's heart sincerely to

212. Love is blind. Love is blind

213. That's all, folks. it is so, you

214. feel sth. in one's bones intuition to

215. It's sink or swim. whether successful or not (thanks to their own)

216. steal one's thunder grab someone else's credit; to steal someone else's way; grab someone else's thunder

217. Where there's smoke, there's fire. no smoke without fire thing; accidental

218. Bad news travels fast. Bad news travels

219. eat one's heart out depressed; sad

220. stand the last of time to accept the test of time

221. a bed of roses boast wishful heart of life

222. Achilles' heel of a person's vulnerability

223. go the distance persist in the end; complete all

224. Cleanliness is next to godliness. Cleanliness is a virtue

225. Knowledge is power. Knowledge is power

226. Love will find a way. love will find a way of

227. Mother knows best. Mother knows best the

228. the bottom line is that ... the basic bottom line ; the end result

229. Beauty is in the eye of the beholder. eye of the beholder

230. Absence makes the heart grow fonder. distance produces beauty; small do not win the wedding

231. Forgive and forget. forgive and forget

232. If it sounds too good to be true, it probably is.

if it sounds like is not true, perhaps not really

233. Those were the days. That was a good time

234. water under the bridge past tense; can not restore the past; thing of the past

235. Monkey see,prada sunglasses 2011, monkey do. suit

236. What one doesn't know won't hurt one. do not know not what

237. There's a time and a place for everything.

come in handy at the right time; timely work

238. You can't win them all. people can not have been lucky; person can not be plain sailing

239. Different strokes for different folks. man has his taste

240. Customers are always right. Customer First

241. give sth. one's best shot every effort

242. If you can't stand the heat, get out of the kitchen.

can not stand the pressure, to leave it

243. If the shoe fits, wear it. If these words right to accept the advice it

244. like two peas in a pod bored with

245. point-blank directly

246. down in the dumps mood stumbled

247. give sb. a piece of one's mind lessons from someone meal

248. If you want a thing done well, do it yourself.

you want to do something,prada handbags 2011, we must own hands

249. Don't spend it all in one place. Do not all in one place

250. go out on a climb to do sth. risked

251. There's no time like the present. there is no more appropriate than it is now time to

252. see / read the handwriting on the wall premonition Ominous

253. Two's company, three is a crowd. two people just fine, and all three are too many

254.Every family has a skeleton in the closet. Every family has its cupboard

255. hardly have time to breathe without breathing time

256. keep your eyes on the ball to concentrate

257. leave no stone unturned to spare no effort; completely

258. I mean it. I mean really

259. make one's hair stand on end with fear; creepy

260. The walls have ears. walls have ears

261. bring home the bacon a living; success

262. They lived happily ever after. they will never live a happy life

263. blow the whistle on sb. / sth. came to light; to stop someone (something)

264. Ignorance is bliss. I do not know is the blessing

265. People who live in glass houses should't throw stones .

they have weaknesses, the total came to light other people's weaknesses

266. pull out all the stops exhausted all the strength

267. take the wind out of one's sails make someone suddenly deflated, humiliating

268. in the seventh heaven of happiness in the incomparable

269. The end justifies the means. for the purpose of unscrupulous

270 . call a spade a spade so fussy

271. A woman's work is never done. housework never ends

272. one's name will be mud person to infamous

273. play second fiddle to sb. as deputy

274. the rhird time's the charm third time is always lucky

275. shape up or ship out look out for themselves, or to left

276. Old dogs can't learn new tricks. elderly is not easy to adapt to new things

277. Life's full fo surprise. Life is full of surprises

278. So quiet that you could hear a pin drop. quiet a pin out of the ground could hear

279. turn back the clock time reversal

280. Fancy meeting you here. how will to see you here

281. bury one 'head in the sand ostrich mentality; do not face the reality

282. You only live once. We only have one

283. Home is where the heart is. Home is always where people miss

284. Has the cat got your tongue? (cat got your tongue Diao leave?) Why do not you speak?

285. When the cat's away. the mice will play. Hades is not, kid jumping

286. Every cloud has a silver lining. cloud has a silver lining; situation improves

287. for the record that formally or explicitly; solemnly declare

288. Good things come to him / her who waits. wine Shen urn at the end

289. Where there's a will. there's a way. Where there is a way

290. sit like a bump on a log sitting with the big wooden general

291. That's the pot calling the kettle black. crow scolded the black pig

292. bang / beat one's head against a brick wall in vain to do something

293. An apple a day keeps the doctor away. eclipse an apple keeps the doctor away

294. To err is human, to forgive divine. err is human, to forgive is rising above commoners

295. Don't count your chickens before they're hatched. wishful thinking do not played too early

296. live and learn live and learn

tag time to recite in English far time